Unlocking the Wild-Type GIST Market: A Challenge for Innovation

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2025-12-26 09:14:25 -

Why is "Wild-Type" GIST a significant unmet need? Approximately 10-15% of GIST cases lack the common KIT or PDGFRA mutations; these are known as "Wild-Type" GIST. Traditional TKIs are often ineffective in these patients, many of whom are younger or have underlying syndromic conditions like neurofibromatosis or Carney-Stratakis syndrome. How is GIST Orphan Drug Research addressing 2024 needs? In...

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