The Evolving Synergy Between Neuromodulation and Pharmacotherapy

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Is Deep Brain Stimulation (DBS) a competitor or an adjunct to drug therapy?

DBS has long been the "last resort" for motor complications. However, the market is moving toward earlier intervention and smarter devices. The relationship between medical devices and therapeutics is shifting from competitive to complementary, as surgical advances allow for lower drug dosages and fewer side effects.

How will Neuromodulation Device Trends affect the therapeutics market in 2025?

The emergence of "sensing" DBS systems—which record brain activity and deliver stimulation only when needed—is a major Neuromodulation Device Trends. In 2024, these closed-loop systems are helping patients maintain stability with significantly reduced levodopa requirements, potentially extending the "honeymoon period" of standard medications into 2025 and beyond.

The growth of non-invasive neuromodulation

Transcranial Magnetic Stimulation (TMS) and other non-invasive techniques are being investigated as adjuncts to drug therapy. These tools offer a bridge for patients who are not candidates for surgery but require more than what oral medications can provide.

  • Rise of directional leads for precision stimulation.
  • Integration of AI to automate DBS programming.
  • Expanding indications for DBS to include gait and balance issues.

Strategic Business Outlook

Healthcare providers should prepare for a multidisciplinary care model in 2025, where the prescription of a drug is often paired with a neuromodulation assessment as part of a holistic "Brain Health" package.

Author: Sofiya Sanjay

Designation: Healthcare Research Consultant, Market Research Future

About: At Market Research Future (MRFR), we enable organizations to unravel complex industries through Cooked Research Reports (CRR), Half-Cooked Research Reports (HCRR), Raw Research Reports (3R), Continuous-Feed Research (CFR), and Market Research & Consulting Services. Our studies across products, technologies, applications, end users, and global to country-level segments help decision-makers see more, know more, and do more.

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